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"Covalent biosensing" enables a one-step, reagent-less, low-cost and highly robust assay of SARS-CoV-2.

Zhang, Kai; Li, Jinlong; Fan, Zhenqiang; Li, Hao; Xu, Jing-Juan.

Chem Commun (Camb) ; 57(82): 10771-10774, 2021 Oct 14.

Article in English | MEDLINE | ID: covidwho-1442812

ABSTRACT

We have established a new protocol for detecting severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) using a peptidomimetic to covalently detect a viral marker protease.

Subject(s)

COVID-19 Testing , COVID-19/diagnosis , SARS-CoV-2 , Viral Proteases/isolation & purification , Biological Assay/economics , Biosensing Techniques/economics , COVID-19/blood , COVID-19/virology , COVID-19 Testing/economics , Cost Savings , Electrochemical Techniques/economics , Humans , Peptidomimetics/chemistry , Tyrosine/chemistry , Viral Proteases/chemistry

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